Little is known about the reproductive habits of this species. A rough-toothed dolphin was bred with a bottlenose dolphin in captivity producing a hybrid offspring.
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Rough-toothed dolphins,
Steno bredanensis , are hunted for food in some regions. They are harpooned in Japan and West Africa. Entanglement in fishing gear poses a threat, and rough-toothed dolphins have been reported caught in purse seines in the eastern tropical Pacific. Others have been reported caught in gillnet and driftnet fisheries in Sri Lanka and Brazil.